Is Social Media More Important than Medical Technology?

Did you know that the seven big Facebook holders, including Mark Zuckerberg, Dustin Moskovitz, and Sean Parker, hold shares totaling $25 billion?  By comparison, all the 12 health care billionaires on last year’s issue of the Forbes 400 Richest People in America had a combined net worth of a measly $28 billion.

Forbes’ Matthew Herper concludes, “There’s not really much doubt: if you want to reach the upper echelons of wealth, creating a social networking site is a better bet than inventing a drug.”  Sound depressing?  Never fear, He had some suggestions as to how the medical device industry could change so that entrepreneurs might break through the glass ceiling and enter the upper stratum of the mega wealthy:

  1. De-emphasize drugs. Right now research in medicine is often centered around medicines. Leland Hartwell, the Nobel laureate who used to run the Fred Hutchison Cancer Institute, used to complain that we could make more progress in cancer by focusing on diagnostics.
  2. Innovate toward disruption: Right now it might cost $2 billion or more and a decade to invent a drug that’s ready to give to people, but does that have to be the case for every drug?
  3. Make more research “pre-competitive:” Too much of the science done at drug companies is locked up inside the silo of a single drug giant, not allowing the free exchange of ideas that leads to real innovations.
  4. Change the way patents work: In the tech business, a device can be protected by hundreds of patents. In the drug industry, you’ve really only got one, and it has a twenty-year life span.   Often, by the time it hits the market, half the patent life is gone. In many cases, the true usefulness and the side effects of a medicine are not apparent until after it becomes generic.

I personally love facebook.  I use it every day.  I post pictures and videos of my kids and keep in touch with people that I probably never would know how to contact if it weren’t for facebook.  However, it seems to me that saving lives and making things that improve people’s quality of living should be worth more than the convenience of being able to share a picture of your kid in his Halloween costume with someone you haven’t seen since high school 25 years ago.

A New Way to Fund Your Medtech Startup

I came across an article entitled “Is crowdfunding a viable option for medical technology startups?” I had no idea what crowdfunding was,  but I thought it sounded interesting.  I actually had to look up the definition of crowdfunding on Wikipedia.  For those of you who are as out of the loop as I am, crowdfunding  describes the collective cooperation, attention and trust by people who network and pool their money and other resources together, usually via the Internet, to support efforts initiated by other people or organizations.

According to Brandon Glenn, for some medtech startups, particularly those with simple medical devices that have already done some research and developed a prototype, crowdfunding could represent a realistic option.  A provision of the JOBS Act enables startups to raise as much as $1 million through crowdfunding and award equity to nonaccredited investors, which is likely to make crowdfunding more attractive to medical technology companies.

Is it worth it to have the hassle of having to deal with hundreds or even thousands of investors? “Crowdfunding will be more successful for biomedical companies if they look to raise a fairly small amount of money to help with technology validation or testing after an early prototype has been created. Before looking to crowdfunding, an entrepreneur should first invest in early development and seek grant funding,” Solomon Nabatiyan, a Northwestern University researcher who co-founded recently launched crowdfunding site TechMoola, said.

I checked out TechMoola, which focuses on technology projects.  It works like this: People sign up for a TechMoola account, put money in their account, look for projects that they like on the site, and then use money out of their account to fund the projects (starting with as little as $5).  I did find a medtech company posted.  Cervia Diagnostic Innovations has their cervical cancer test listed.  According to the stats, it had a total of $548 pledged so far.  From a business owner’s standpoint, it seems to me like trying to fill a gallon jug using a medicine dropper, but I suppose every little bit helps.

 

iPhone ECG- From Humans to Horses

It makes me think of the riddles we used to tell in elementary school.  “I can be carried with you everywhere, used to communicate with others, used on humans and horses, and I diagnose serious cardiac problems.  What am I?”

A recent study utilizing 54 patients reveiwed the AliveCor iPhone ECG.  The iPhone ECG can be used for everything from consumer use, clinical diagnostics, to veterinary applications.

In the study, the participants were provided with a case and an app to use with their iPhone. Without receiving instructions on how to use the product, the participants were told to go and to record their ECG at least once per day.  Over the course of eight weeks, about 1500 ECGs were recorded and transmitted—about 90% of which were clinically useful.

When asked about the veterinary applications, David Albert, MD, inventor of the device and chief medical officer of AliveCor says, “I can absolutely tell you that our product from the top of the veterinary cardiology, they find it extremely useful on dogs, cats, and even horses. The iPhone ECG is going to be used by veterninarians, by electrophysiologists, cardiologists, internists, family medicine doctors, ER doctors, EMTs, paramaedics, home health nurses, medics, and then by patients themselves,” Albert adds.

Perhaps the above riddle won’t stick with someone for 35 years like my personal favorite, “What’s black and white and red all over?” (a newspaper),  but it certainly has more practical application in the real world.

 

 

Any Room Can Be an OR

A new product called Arc Sterile from IMEX brings purified, surgical quality air to just about any environment.  The portable system can be easily wheeled and quickly setup over a surgical table, turning any room into an OR.  It features HEPA filters to clean the air and fans that sweep the environment free of unwanted particles.

I’ve talked before about my favorite medical drama, Grey’s Anatomy.  In the show, there always seems to be a shortage of operating rooms. This leaves the doctors having to wait until a room opens up, every minute that passes putting their patient in grave danger of not making it, and thus adding to the drama.  If real life hospital situations are anything like this show, an Arc Sterile would come in handy as doctors trapped in a stuck elevator attempt to bravely save their dying patient by doing a heart surgery with nothing to work with but their bare hands and a couple of tools that the other doctors are able to slip through a small crack between the elevator doors which they have managed to pry open. (That is, provided someone had the foresight to strategically store an Arc Sterile in a secret compartment in the elevator ahead of time.)  OK- well hopefully reality would be a bit more realistic.  Nonetheless, it is still a valuable idea.

Medical Devices from Toys

If your house is like mine, and you have lots of toys laying around that your kids no longer play with, perhaps there is another option besides sending them off to Goodwill.

Jose Gomez-Marquez, director of the Director of the IIH (Innovations in International Health) Lab at MIT, is heading up MIT’s Little Devices group, dedicated to design, invention, and policy toward DIY health technologies.  Created with the healthcare needs of the developing world in mind, the MEDIKit (Medical Education Design and Invention Kit) allows medical professionals to design their own medical devices using easy-to-assemble modular components. The MEDIKit allows users to customize and quickly assemble medical devices that address the challenges of work environments in many developing nations.

MEDIKits are designed to demonstrate that such high cost equipment may be more of a luxury than a necessity by teaching medical staff to adopt other, potentially cheaper technologies to accomplish the same purpose. LEGOs can be used as breadboards to create wet lab circuits, a bicycle pump can be adapted into a nebulizer for asthmatic patients, Gomez-Marquez and his team really believe the possibilities are limited only by users’ ingenuity.

What could you design out of your children’s toys?  All it takes is a little creativity.  Look at it this way, you can either do something inventive to help humanity, or plan a garage sale, which I know I certainly don’t have the patience for.

 

 

 

A New Type of Vision

There have recently been a couple of interesting apps developed for the visually impaired.

Mario Romero, postdoctoral fellow at Georgia Tech, came up with the idea to develop BrailleTouch, an app that allows folks to type on the touchscreen without seeing it at all. The application works by putting the 6 dots of a braille character on the screen in landscape mode with 3 on each side. Three fingers from each hand then press in the appropriate patterns to create the desired characters. There is audio feedback to confirm the correct input and the screen flips regardless of orientation so a user does not have to worry about the phone being “upside-down.”

Studying math while blind is a difficult proposition because many concepts are visually represented using charts, graphs, and other methods. To help address this problem, Engineers at Vanderbilt University have developed an Android app for touchscreen tablets that essentially turns visual objects into tactile ones. When the user touches a line or other object on the screen, the program activates the built-in vibrator so that the object can be felt.

I am always impressed when people can step outside of their own world and anticipate the needs of someone else.  I am ashamed to say, it has never even occurred to me to think that touchscreens would be difficult for blind people to use.  I can’t help but imagine what other technology could be developed if we all got our heads out of the sand and took more interest in what was happening around us.  Ironically, that would probably involve getting out of our self-imposed electronic worlds of texting, facebooking, and chatting online and actually observing the things that are going on in real life.

Insulin Pump Hacking

This is something I never would have considered possible, but it certainly does make you stop and think…

With a radio device, Barnaby Jack, a researcher with McAfee Inc, showed how a common insulin pump — which is implanted inside the body of a diabetic patient to deliver prescribed doses of the chemical into the bloodstream — can be hacked to deliver doses higher than required, triggering fatal consequences.

Although this may seem like fodder for the latest thriller novel, it is in reality rather frightening. It goes to show you that although innovation is great, with it comes greater responsibility.

Descend Into an Online World of Myth, Magic, and Limitless Adventure While at the Same Time Boosting Your Cognitive Functioning

Worried you’re going to retire and have nothing to do?  Perhaps you can pull yourself up to the computer and whittle away the hours…

Researchers from North Carolina State University’s Gains Through Gaming laboratory have found that playing the massive multiplayer online video game World of Warcraft (WoW) appeared to boost cognitive functioning in older adults. The researchers hypothesized that playing a cognitively complex game such as WoW, which requires multitasking and extensive use of a number of cognitive skills such as map reading, planning and tracking of multiple status indicators, could boost the cognitive performance of the elderly.

My mom spent the last six years of her life in assisted living facilities and nursing homes.  It seems that the inhabitants, including my mom, spent most of their time sitting around and staring into space or sleeping.  It makes sense that it would be more productive and beneficial for them to be engaging in an activity in which they have think and plan.  Although, I am left to ponder, do I really want grandma to be “witnessing zeppelins flying over smoldering battlefields, facing the mighty Dragon of Blackrock Spire, and cleansing the undead from the looming ziggurats of Stratholme?”

 

Beam Me Up

Trekkies, rejoice! The dream of a Star Trek-style hand held medical scanner is now closer due to a new development in electromagnetic Terahertz (THz) wave technology, also known as T-rays. This technology, also seen in full-body security scanners, is currently able to detect very small and otherwise hidden biological phenomena such as increased blood flow around tumorous growths.

‘T-rays promise to revolutionize medical scanning to make it faster and more convenient, potentially relieving patients from the inconvenience of complicated diagnostic procedures and the stress of waiting for accurate results.’

Now, don’t kid yourself into thinking that this means that we will also have transporters and phasers anytime in the near future.  I suppose my dream of being able to avoid the hassles of airline travel by beaming myself to a tropical destination will have to wait for another day, although somehow, in my mind it does seem a bit more plausible.

 

Driving a Wheel Chair With Your Tongue

This is a really cool example of  using technology to come up with a unique solution to a problem:

The newest prototype of the Tongue Drive System which enables quadriplegics the ability to operate wheelchairs and other devices by moving their tongues,  makes use of a dental retainer with sensors to help control the system.The embedded sensors within the retainer track the movements of a small magnet attached to the tongue.

 

 

Is It a Medical Device, Or Not?

Is it a medical device, or not?

Although the definition of a medical device hasn’t changed, the issue is the intended use of certain mobile health products that previously weren’t classified as medical devices. Now, because of the way certain products are being packaged and marketed, they could potentially fall into the category of a medical device, and thus would need to conform to FDA requirements. Part of the problem is that some manufacturers of medical apps may not even know that they are making a regulated device, according to comments that AdvaMed submitted to FDA in October. The association recommended that FDA reword its document into “plain language” as a result. “If you have an application that works on an iPad and the app says that it specifically helps diagnose a certain disease, then the app becomes a medical device,” says Streed. “The iPad is not considered a medical device, but the software would be. However, if an iPad was called a medical iPad, [for example], and the application could only be used on the medical iPad and is marketed as a medical iPad for use and diagnosis [of a disease], then it would be considered a medical device.”

I don’t know if I’m more confused or less confused…

Prosthetic Lego Arm? Really?

As I survey my son’s room with the hundreds of tiny plastic pieces scattered all over and prepare to launch into my “You need to pick up your legos” diatribe, the last thing on my mind is usually medical device product development, but perhaps I will see things differently from now on.

Max Shepherd developed and built the 12 degree of freedom prosthetic arm from Lego components as a means to accurately mimic the full range of motion of a normal human arm and hand. The hand movements are powered using Lego pneumatics while the wrist pronation/supination, wrist flexion/extension, and elbow flexion/extension are powered by Lego motors.

Does this make me feel any better about the plastic parts that seem to find their way over every inch of my house, making it a mine field to anyone trying to navigate it in bare feet, especially in the dark?  Not really…

Clean Hands, Warm Computer

Recently, a group of psychologists from Germany and the United Kingdom evaluated whether a web-based intervention could affect the frequency of hand-washing in the home.  The team of psychologists concluded strong evidence now exists that web-based interventions could be an effective way to promote hand hygiene in the home.  It was determined that the intervention had “positive indirect effects on change in hand-washing via intentions”.

Does this mean that if I were to send my child messages about washing his hands on the web, he would be more likely to soap up than he is when I constantly nag him about it? What about other things, like cleaning his room or doing his math? Could there be “positive indirect effects” on with web-based intervention in these areas also?  Well, it’s certainly something to consider…

Who Needs Human Interaction, Anyway?

Can Texting Keep Teens From Becoming Depressed?”  This title caught my eye.

Researchers at the University of Auckland in New Zealand used these concepts to develop and test an intervention for adolescents focused on preventing depression.  The intervention was designed around 15 key messages derived from cognitive behavior therapy.  These positive and encouraging messages were delivered automatically via mobile phones twice daily for 9 weeks by means of text, video, cartoons, and mobile website.  Two types of controls were used, including a control program with the same number and types of messages on varying topics and a randomized controlled trial performed in surrounding high schools of the Auckland, New Zealand area.

The study concluded that key messages from cognitive behavioral therapy can indeed be effectively delivered by mobile phone, and young people reported that they found this to be helpful.

I’ve blogged about smart phones being capable of inferring user emotion.  Then there were the apps that help you to work through your phobias.  Here is yet another example of how smartphones are replacing basic human interaction when it comes to our emotional issues. Are we that self-absorbed that we don’t want to take the time to interact with our children ourselves and instead would prefer to entrust their well-being to a mechanical device?

Cockroaches Produce Electricity

Researchers at Case Western Reserve University managed to generate electricity from naturally occurring chemicals within the abdomen of the false death’s head cockroach. How does this help us, you might ask?  The thought is that if we can learn to harvest energy from within the human body, we may spur the development of a new generation of implantable devices that can work as long as the patient is alive, and therefore producing electricity, without requiring bulky batteries, a typical stumbling block for biomedical engineers.

I’m all for advances in technology, but I can’t seem to wrap my mind around this one.  Part of the problem is probably that I am a cockroachaphobe.  I don’t mind most bugs (except spiders), but I am having troubles getting over the fact that I find cockroaches creepy, ugly, and disgusting. Why couldn’t a cute bug, like a lady bug, have chemicals capable of producing electricity in its belly?