Back in 2006, a momentous event happened in Indiana’s medical device startup scene. Upstart Suros Surgical was acquired by Massachusetts-based Hologic for a ridiculous amount of money. Ever since then, Suros Surgical has served as a poster child for all other aspiring medical device startups in Indiana. And at the same time, many people also assumed that once acquired, the jobs established in Indianapolis around Suros would some day probably go away.

Fast forward six years later to present day. It was announced yesterday that Hologic will be closing its Indianapolis operations within the next 18 months. I have several friends who work at the Indy site–all great folks who I’m quite sure will land on their feet. But Suros / Hologic in central Indiana has been important to the “life science movement” in these parts. For years, it has represented the success story of entrepreneurs who literally started in a garage that eventually got acquired for hundreds of millions of dollars. And soon, Suros will fade off into the sunset.

For years, I’ve been wondering who the next Suros will be in Indiana. Or even if there will be a next Suros in Indiana.

If you want to read more about the few details on this story, you can check out IBJ or IndyStar.